Screening for potential prophylactics targeting sporozoite motility through the skin

Abstract Background Anti-malarial compounds have not yet been identified that target the first obligatory step of infection in humans: the migration of Plasmodium sporozoites in the host dermis. This movement is essential to find and invade a blood vessel in order to be passively transported to the...

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Bibliographic Details
Main Authors: Ross G. Douglas, Miriam Reinig, Matthew Neale, Friedrich Frischknecht
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Malaria Journal
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12936-018-2469-0