Aromatic amino acid metabolites alter interferon signaling and influenza pathogenesis

The ability of gut microbial metabolites to influence the host is increasingly recognized. The microbiota extensively metabolizes the three aromatic amino acids, tryptophan, tyrosine, and phenylalanine. Previously we have found that a metabolite of tyrosine, 4-OH-phenylpropionic acid, can enhance ty...

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Bibliographic Details
Main Authors: Gautam Anand, Colin Clark-Dinovo, Alexandra M. Perry, Victoria M. Goodwin, Emma St. Raymond, Sonia Sakleshpur, Ashley L. Steed
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1232573/full