Myristoylated, alanine-rich C-kinase substrate (MARCKS) regulates toll-like receptor 4 signaling in macrophages

Abstract MARCKS (myristoylated alanine-rich C-kinase substrate) is a membrane-associated protein expressed in many cell types, including macrophages. MARCKS is functionally implicated in cell adhesion, phagocytosis, and inflammation. LPS (lipopolysaccharide) triggers inflammation via TLR4 (toll-like...

Full description

Bibliographic Details
Main Authors: Jiraphorn Issara-Amphorn, Virginie H. Sjoelund, Margery Smelkinson, Sebastian Montalvo, Sung Hwan Yoon, Nathan P. Manes, Aleksandra Nita-Lazar
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-46266-x