Ebola Virus Glycoprotein Induces an Innate Immune Response In vivo via TLR4

Ebola Virus Glycoprotein Induces an Innate Immune Response In vivo via TLR4

Ebola virus (EBOV), a member of the Filoviridae family, causes the most severe form of viral hemorrhagic fever. Although no FDA licensed vaccine or treatment against Ebola virus disease (EVD) is currently available, Ebola virus glycoprotein (GP) is the major antigen used in all candidate Ebola vacci...

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Bibliographic Details
Main Authors: Chih-Yun Lai, Daniel P. Strange, Teri Ann S. Wong, Axel T. Lehrer, Saguna Verma
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Microbiology
Subjects:
Ebola virus
glycoprotein
innate immunity
TLR4
Ebola vaccine
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.01571/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.01571/full

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