The Link between Activities of Hepatic 11beta-Hydroxysteroid Dehydrogenase-1 and Monoamine Oxidase-A in the Brain Following Repeated Predator Stress: Focus on Heightened Anxiety

The Link between Activities of Hepatic 11beta-Hydroxysteroid Dehydrogenase-1 and Monoamine Oxidase-A in the Brain Following Repeated Predator Stress: Focus on Heightened Anxiety

We investigated the presence of a molecular pathway from hepatic 11-βHSD-1 to brain MAO-A in the dynamics of plasma corticosterone involvement in anxiety development. During 14 days following repeated exposure of rats to predator scent stress for 10 days, the following variables were measured: hepat...

Full description

Bibliographic Details
Main Authors: Vadim Tseilikman, Maxim Lapshin, Igor Klebanov, George Chrousos, Maria Vasilieva, Anton Pashkov, Julia Fedotova, David Tseilikman, Vladislav Shatilov, Eugenia Manukhina, Olga Tseilikman, Alexey Sarapultsev, H. Fred Downey
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
anxiety-like behavior
11-βHSD-1
corticosterone
MAO-A
mathematical modeling
norepinephrine
Online Access:https://www.mdpi.com/1422-0067/23/9/4881

Internet

https://www.mdpi.com/1422-0067/23/9/4881

Similar Items