Identification of neutrophil extracellular trap-driven gastric cancer heterogeneity and C5AR1 as a therapeutic target

Identification of neutrophil extracellular trap-driven gastric cancer heterogeneity and C5AR1 as a therapeutic target

Neutrophil extracellular traps (NETs) are implicated in gastric cancer (GC) growth, metastatic dissemination, cancer-associated thrombosis, etc. This work is conducted to elucidate the heterogeneity of NETs in GC. The transcriptome heterogeneity of NETs is investigated in TCGA-STAD via a consensus c...

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Bibliographic Details
Main Authors: Zhao Jing, Li Xiangyu, Li Liming, Chen Beibei, Xu Weifeng, He Yunduan, Chen Xiaobing
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2024-03-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
neutrophil extracellular trap
gastric cancer
heterogeneity
personalized therapy
C5AR1
treatment target
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2023290

Internet

https://www.sciengine.com/doi/10.3724/abbs.2023290

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