Theoretical Investigation on the ESIPT Process and Detection Mechanism for Dual-Proton Type Fluorescent Probe

Theoretical Investigation on the ESIPT Process and Detection Mechanism for Dual-Proton Type Fluorescent Probe

Recently, a new fluorescent probe AE-Phoswas reported to detect the activity of alkaline phosphatases (ALP) in different living cell lines. Here, we present an in-depth computational analysis of the mechanism and source of the fluorescence of the AE-Phos probe. There is an intermediate product (AE-O...

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Bibliographic Details
Main Authors: Yunjian Cao, Xiangrui Yu, Chaofan Sun, Jingang Cui
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
alkaline phosphatase
fluorescence probe
double proton transfer
time-dependent density functional theory
Online Access:https://www.mdpi.com/1422-0067/23/4/2132

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https://www.mdpi.com/1422-0067/23/4/2132

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