Targeting the Platelet-Activating Factor Receptor (PAF-R): Antithrombotic and Anti-Atherosclerotic Nutrients

Targeting the Platelet-Activating Factor Receptor (PAF-R): Antithrombotic and Anti-Atherosclerotic Nutrients

Platelet-activating factor (PAF) is a lipid mediator that interacts with its receptor (PAF-R) to carry out cell signalling. However, under certain conditions the binding of PAF to PAF-R leads to the activation of pro-inflammatory and prothrombotic pathways that have been implicated in the onset and...

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Bibliographic Details
Main Authors: Rajendran Harishkumar, Sakshi Hans, Janelle E. Stanton, Andreas M. Grabrucker, Ronan Lordan, Ioannis Zabetakis
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Nutrients
Subjects:
platelet-activating factor
platelet-activating factor receptor
polar lipids
antithrombotic activity
inflammation
atherosclerosis
Online Access:https://www.mdpi.com/2072-6643/14/20/4414

Internet

https://www.mdpi.com/2072-6643/14/20/4414

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