The role of sperm-specific glyceraldehyde-3-phosphate dehydrogenase in the development of pathologies—from asthenozoospermia to carcinogenesis

The role of sperm-specific glyceraldehyde-3-phosphate dehydrogenase in the development of pathologies—from asthenozoospermia to carcinogenesis

The review considers various aspects of the influence of the glycolytic enzyme, sperm-specific glyceraldehyde-3-phosphate dehydrogenase (GAPDS) on the energy metabolism of spermatozoa and on the occurrence of several pathologies both in spermatozoa and in other cells. GAPDS is a unique enzyme normal...

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Bibliographic Details
Main Authors: Irina Naletova, Elena Schmalhausen, Barbara Tomasello, Denis Pozdyshev, Francesco Attanasio, Vladimir Muronetz
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Molecular Biosciences
Subjects:
GAPDS
GAPDH
sperm motility
melanoma
neurodegenerative diseases
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1256963/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2023.1256963/full

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