Non-canonical Wnt/Ca2+ signaling is essential to promote self-renewal and proliferation in colon cancer stem cells

Non-canonical Wnt/Ca2+ signaling is essential to promote self-renewal and proliferation in colon cancer stem cells

IntroductionCancer Stem Cells (CSC) are responsible for maintaining tumor growth, chemoresistance, and metastasis. Therefore, understanding their characteristics is critical to progress in cancer therapy. While the contribution of the canonical Wnt/b-catenin signaling in both normal and CSCs had bee...

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Bibliographic Details
Main Authors: Miguel Angel Sarabia-Sánchez, Angela Patricia Moreno-Londoño, María Cristina Castañeda-Patlán, Eduardo Alvarado-Ortiz, Juan Carlos Martínez-Morales, Martha Robles-Flores
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Oncology
Subjects:
cancer stem cell
non-canonical Wnt/Ca2+ signaling
PLC
NFAT
tumor spheres
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1121787/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1121787/full

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