DMDRMR promotes angiogenesis via antagonizing DAB2IP in clear cell renal cell carcinoma

Abstract Clear cell renal cell carcinoma (ccRCC) patients are highly angiogenic and treated by targeted therapies against VEGFA/VEGFR signaling pathway. However, tumors with such targeted therapies remain a significant clinic challenge. Understanding the underlying mechanism against angiogenesis is...

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Bibliographic Details
Main Authors: Yumeng Zhu, Xiaojun Liu, Yang Wang, Yongbo Pan, Xiaoqi Han, Bo Peng, Xu Zhang, Shaoxi Niu, He Wang, Qinong Ye, Yinmin Gu, Shan Gao
Format: Article
Language:English
Published: Nature Publishing Group 2022-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-04898-3