DMDRMR promotes angiogenesis via antagonizing DAB2IP in clear cell renal cell carcinoma
Abstract Clear cell renal cell carcinoma (ccRCC) patients are highly angiogenic and treated by targeted therapies against VEGFA/VEGFR signaling pathway. However, tumors with such targeted therapies remain a significant clinic challenge. Understanding the underlying mechanism against angiogenesis is...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-05-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-022-04898-3 |