Losartan and magnesium sulfate administration reduce gentamicin-induced nephrotoxicity in rat model

Losartan and magnesium sulfate administration reduce gentamicin-induced nephrotoxicity in rat model

Background: Nephrotoxicity is the most known side effect of gentamicin. In addition, renin angiotensin system (RAS) plays an important role in the pathogenesis of renal injury and nephrotoxicity. Hypomagnesaemia is other complication of gentamicin. Previous studies reported that magnesium plays an i...

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Bibliographic Details
Main Authors: Fatemeh Kourkinejad Gharaei, Tahereh Safari, Abbass Ali Niazi, Meysam Zeynali Bujani
Format: Article
Language:English
Published: Society of Diabetic Nephropathy Prevention 2019-04-01
Series:Journal of Nephropathology
Subjects:
gentamicin
nephrotoxicity
magnesium sulfate
losartan
renal function
renin angiotensin system
Online Access:https://nephropathol.com/PDF/jnp-8-e16.pdf

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https://nephropathol.com/PDF/jnp-8-e16.pdf

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