Development of Adenovirus Containing Liposomes Produced by Extrusion vs. Homogenization: A Comparison for Scale-Up Purposes

Development of Adenovirus Containing Liposomes Produced by Extrusion vs. Homogenization: A Comparison for Scale-Up Purposes

Adenovirus (Ad) is a widely studied viral vector for cancer therapy as it can be engineered to cause selective lysis of cancer cells. However, Ad delivery is limited in treating cancers that do not have coxsackievirus and adenovirus receptors (CAR). To overcome this challenge, Ad-encapsulated liposo...

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Bibliographic Details
Main Authors: Jaimin R. Shah, Tao Dong, Abraham T. Phung, Tony Reid, Christopher Larson, Ana B. Sanchez, Bryan Oronsky, Sarah L. Blair, Omonigho Aisagbonhi, William C. Trogler, Andrew C. Kummel
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Bioengineering
Subjects:
adenovirus
cancer
coxsackievirus and adenovirus receptor
liposome
transduction
extrusion
Online Access:https://www.mdpi.com/2306-5354/9/11/620

Internet

https://www.mdpi.com/2306-5354/9/11/620

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