2-Methoxyestradiol Inhibits Radiation-Induced Skin Injuries

2-Methoxyestradiol Inhibits Radiation-Induced Skin Injuries

Radiation-induced skin injury (RISI) is a main side effect of radiotherapy for cancer patients, with vascular damage being a common pathogenesis of acute and chronic RISI. Despite the severity of RISI, there are few treatments for it that are in clinical use. 2-Methoxyestradiol (2-ME) has been repor...

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Bibliographic Details
Main Authors: Ji-Hee Kim, Jae-Kyung Nam, A-Ram Kim, Min-Sik Park, Hae-June Lee, Joonho Park, Joon Kim, Yoon-Jin Lee
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
2-Methoxyestradiol
radiation-induced skin injury
HIF 1-α
vascular fibrosis
Online Access:https://www.mdpi.com/1422-0067/23/8/4171

Internet

https://www.mdpi.com/1422-0067/23/8/4171

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