Role of nitrite, urate and pepsin in the gastroprotective effects of saliva

Dietary nitrate is now recognized as an alternative substrate for nitric oxide (•NO) production in the gut. This novel pathway implies the sequential reduction of nitrate to nitrite, •NO and other bioactive nitrogen oxides but the physiological relevance of these oxidants has remained elusive. We ha...

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Bibliographic Details
Main Authors: Bárbara S. Rocha, Jon O Lundberg, Rafael Radi, João Laranjinha
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231716300271