PD-L1 expression levels in mesenchymal stromal cells predict their therapeutic values for autoimmune hepatitis

PD-L1 expression levels in mesenchymal stromal cells predict their therapeutic values for autoimmune hepatitis

Abstract Background Autoimmune hepatitis is a chronic inflammatory hepatic disorder with no effective treatment. Mesenchymal stromal cells (MSCs) have emerged as a promising treatment owing to their unique advantages. However, their heterogeneity is hampering use in clinical applications. Methods Wh...

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Bibliographic Details
Main Authors: Xilong Bai, Tingwei Chen, Yuqi Li, Xiaofan Ge, Caie Qiu, Huili Gou, Sili Wei, Tingting Liu, Wei Yang, Liting Yang, Yingmin Liang, Zhansheng Jia, Liangshan Lv, Tianqing Li
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stromal cells
Cellular heterogeneity
PD-L1
Immunoregulation
Autoimmune hepatitis
Online Access:https://doi.org/10.1186/s13287-023-03594-z

Internet

https://doi.org/10.1186/s13287-023-03594-z

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