Apigenin Ameliorates Hyperuricemia and Renal Injury through Regulation of Uric Acid Metabolism and JAK2/STAT3 Signaling Pathway

Apigenin Ameliorates Hyperuricemia and Renal Injury through Regulation of Uric Acid Metabolism and JAK2/STAT3 Signaling Pathway

Hyperuricemia (HUA) is a kind of metabolic disease with high incidence that still needs new countermeasures. Apigenin has uric-lowering and kidney-protective activities, but how apigenin attenuates HUA and renal injury remains largely unexploited. To this end, an acute HUA mouse model was establishe...

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Bibliographic Details
Main Authors: Tianyuan Liu, Huimin Gao, Yueyi Zhang, Shan Wang, Meixi Lu, Xuan Dai, Yage Liu, Hanfen Shi, Tianshu Xu, Jiyuan Yin, Sihua Gao, Lili Wang, Dongwei Zhang
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Pharmaceuticals
Subjects:
hyperuricemia
apigenin
uric acid
molecular docking
JAK2/STAT3 signaling
renal injury
Online Access:https://www.mdpi.com/1424-8247/15/11/1442

Internet

https://www.mdpi.com/1424-8247/15/11/1442

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