HDX-MS: An Analytical Tool to Capture Protein Motion in Action

Virtually all protein functions in the cell, including pathogenic processes, require coordinated motion of atoms or domains, i.e., conformational dynamics. Understanding protein dynamics is therefore critical both for drug development and to learn about the underlying molecular causes of many diseas...

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Bibliographic Details
Main Authors: Dominic Narang, Cristina Lento, Derek J. Wilson
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/8/7/224