A novel 5-Fluorocuracil multiple-nanoemulsion used for the enhancement of oral bioavailability in the treatment of colorectal cancer

5-Fluorouracil (5-FU) is a drug of choice for colorectal-cancer. But oral therapeutic efficacy of 5-FU is restricted due to their very little bioavailability because of poor membrane permeability and GIT-absorption. We have developed a multiple nanoemulsion (w/o/w i.e. 5-FU-MNE) in which 5-FU incorp...

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Bibliographic Details
Main Authors: Niyaz Ahmad, Ahmed A. Albassam, Mohd Faiyaz Khan, Zabih Ullah, Taysser Mohammed Buheazah, Hussain Salman AlHomoud, Hassan Ali Al-Nasif
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Saudi Journal of Biological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1319562X22000936