A novel 5-Fluorocuracil multiple-nanoemulsion used for the enhancement of oral bioavailability in the treatment of colorectal cancer
5-Fluorouracil (5-FU) is a drug of choice for colorectal-cancer. But oral therapeutic efficacy of 5-FU is restricted due to their very little bioavailability because of poor membrane permeability and GIT-absorption. We have developed a multiple nanoemulsion (w/o/w i.e. 5-FU-MNE) in which 5-FU incorp...
Main Authors: | Niyaz Ahmad, Ahmed A. Albassam, Mohd Faiyaz Khan, Zabih Ullah, Taysser Mohammed Buheazah, Hussain Salman AlHomoud, Hassan Ali Al-Nasif |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-05-01
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Series: | Saudi Journal of Biological Sciences |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1319562X22000936 |
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