Potent SARS-CoV-2-Specific T Cell Immunity and Low Anaphylatoxin Levels Correlate With Mild Disease Progression in COVID-19 Patients

Potent SARS-CoV-2-Specific T Cell Immunity and Low Anaphylatoxin Levels Correlate With Mild Disease Progression in COVID-19 Patients

T cells play a fundamental role in the early control and clearance of many viral infections of the respiratory system. In SARS-CoV-2-infected individuals, lymphopenia with drastically reduced CD4+ and CD8+ T cells correlates with Coronavirus disease 2019 (COVID-19)-associated disease severity and mo...

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Bibliographic Details
Main Authors: Eliott Lafon, Gabriel Diem, Christina Witting, Viktoria Zaderer, Rosa Maria Bellmann-Weiler, Markus Reindl, Angelika Bauer, Andrea Griesmacher, Vilmos Fux, Gregor Hoermann, Carl Miller, August Zabernigg, Ewald Wöll, Doris Wilflingseder, Cornelia Lass-Flörl, Wilfried Posch
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
T cell immunity
neutralizing Abs
anaphylatoxin
ELISpot assay
COVID-19
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.684014/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.684014/full

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