Oncogenic Kras-Mediated Cytokine CCL15 Regulates Pancreatic Cancer Cell Migration and Invasion through ROS

Oncogenic Kras-Mediated Cytokine CCL15 Regulates Pancreatic Cancer Cell Migration and Invasion through ROS

Pancreatic ductal adenocarcinoma (PDAC) is well known for its high death rate due to prompt cancer metastasis caused by cancer cell migration and invasion within the early stages of its development. Here, we reveal a new function of cytokine CCL15, namely the upregulation of PDAC cell migration and...

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Bibliographic Details
Main Authors: Justin K. Messex, Kiyah L. A. Adams, William G. Hawkins, David DeNardo, Nabeel Bardeesy, Daniel D. Billadeau, Geou-Yarh Liou
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cancers
Subjects:
CCL15
Kras<sup>G12D</sup>
pancreatic ductal adenocarcinoma
cell migration
cell invasion
metastasis
Online Access:https://www.mdpi.com/2072-6694/14/9/2153

Internet

https://www.mdpi.com/2072-6694/14/9/2153

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