Predicting response to preoperative chemotherapy agents by identifying drug action on modeled microRNA regulation networks.

Identifying patients most responsive to specific chemotherapy agents in neoadjuvant settings can help to maximize the benefits of treatment and minimize unnecessary side effects. Metagene approaches that predict response based on gene expression signatures derived from an associative analysis of cli...

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Bibliographic Details
Main Authors: Lida Zhu, Juan Liu, Fengji Liang, Simon Rayner, Jianghui Xiong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4029965?pdf=render