Diabetic kidney disease induces transcriptome alterations associated with angiogenesis activity in human mesenchymal stromal cells

Diabetic kidney disease induces transcriptome alterations associated with angiogenesis activity in human mesenchymal stromal cells

Abstract Background Therapeutic interventions that optimize angiogenic activities may reduce rates of end-stage kidney disease, critical limb ischemia, and lower extremity amputations in individuals with diabetic kidney disease (DKD). Infusion of autologous mesenchymal stromal cells (MSC) is a promi...

Full description

Bibliographic Details
Main Authors: Xiaohui Bian, Sabena M. Conley, Alfonso Eirin, Eric A. Zimmerman Zuckerman, Anastasia L. Smith, Cody C. Gowan, Zachary K. Snow, Tambi Jarmi, Houssam Farres, Young M. Erben, Albert G. Hakaim, Matthew A. Dietz, Abba C. Zubair, Saranya P. Wyles, Joy V. Wolfram, Lilach O. Lerman, LaTonya J. Hickson
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Stem Cell Research & Therapy
Subjects:
Chronic kidney disease
Diabetes mellitus
Diabetic nephropathy
Ischemic limb disease
Mesenchymal stromal cells
Regenerative medicine
Online Access:https://doi.org/10.1186/s13287-023-03269-9

Internet

https://doi.org/10.1186/s13287-023-03269-9

Similar Items