PTX3 Regulation of Inflammation, Hemostatic Response, Tissue Repair, and Resolution of Fibrosis Favors a Role in Limiting Idiopathic Pulmonary Fibrosis

PTX3 Regulation of Inflammation, Hemostatic Response, Tissue Repair, and Resolution of Fibrosis Favors a Role in Limiting Idiopathic Pulmonary Fibrosis

PTX3 is a soluble pattern recognition molecule (PRM) belonging to the humoral innate immune system, rapidly produced at inflammatory sites by phagocytes and stromal cells in response to infection or tissue injury. PTX3 interacts with microbial moieties and selected pathogens, with molecules of the c...

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Bibliographic Details
Main Authors: Andrea Doni, Alberto Mantovani, Barbara Bottazzi, Remo Castro Russo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
PTX3
inflammation
hemostasis
resolution
fibrosis
IPF
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.676702/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.676702/full

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