Schisandrin A regulates the Nrf2 signaling pathway and inhibits NLRP3 inflammasome activation to interfere with pyroptosis in a mouse model of COPD

Schisandrin A regulates the Nrf2 signaling pathway and inhibits NLRP3 inflammasome activation to interfere with pyroptosis in a mouse model of COPD

Abstract Chronic obstructive pulmonary disease (COPD) is a serious chronic lung disease. Schisandrin A (SchA) is one of the most important active ingredients in Schisandra chinensis and has been used to treat various lung diseases in several countries. Here, we studied the pharmacological effect of...

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Bibliographic Details
Main Authors: Jiamin Zeng, Sida Liao, Zhu Liang, Caiping Li, Yuewen Luo, Kexin Wang, Dapeng Zhang, Lan Lan, Suzhen Hu, Wanyan Li, Ran Lin, Zichen Jie, Yuanlong Hu, Shiting Dai, Zhimin Zhang
Format: Article
Language:English
Published: BMC 2023-07-01
Series:European Journal of Medical Research
Online Access:https://doi.org/10.1186/s40001-023-01190-8

Internet

https://doi.org/10.1186/s40001-023-01190-8

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