Posttranslational Modifications in PD-L1 Turnover and Function: From Cradle to Grave

Posttranslational Modifications in PD-L1 Turnover and Function: From Cradle to Grave

Programmed death-ligand 1 (PD-L1) is one of the most classic immune checkpoint molecules. Cancer cells express PD-L1 to inhibit the activity of effector T cells’ cytotoxicity through programmed death 1 (PD-1) engagement in exposure to inflammatory cytokines. PD-L1 expression levels on cancer cells m...

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Bibliographic Details
Main Authors: Xinfang Yu, Wei Li, Ken H. Young, Yong Li
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Biomedicines
Subjects:
programmed death-ligand 1
programmed death 1
posttranslational modifications
stability
translocation
immunotherapy
Online Access:https://www.mdpi.com/2227-9059/9/11/1702

Internet

https://www.mdpi.com/2227-9059/9/11/1702

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