Multi-step recognition of potential 5' splice sites by the Saccharomyces cerevisiae U1 snRNP

Multi-step recognition of potential 5' splice sites by the Saccharomyces cerevisiae U1 snRNP

In eukaryotes, splice sites define the introns of pre-mRNAs and must be recognized and excised with nucleotide precision by the spliceosome to make the correct mRNA product. In one of the earliest steps of spliceosome assembly, the U1 small nuclear ribonucleoprotein (snRNP) recognizes the 5' sp...

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Bibliographic Details
Main Authors: Sarah R Hansen, David S White, Mark Scalf, Ivan R Corrêa, Lloyd M Smith, Aaron A Hoskins
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-08-01
Series:eLife
Subjects:
splicing
RNA
snRNP
single-molecule fluorescence
CoSMoS
spliceosome
Online Access:https://elifesciences.org/articles/70534

Internet

https://elifesciences.org/articles/70534

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