Generation of multi-gene knockout rabbits using the Cas9/gRNA system

The prokaryotic clustered regularly interspaced short palindromic repeat (CRISPR)-associated system (Cas) is a simple, robust and efficient technique for gene targeting in model organisms such as zebrafish, mice and rats. In this report, we applied CRISPR technology to rabbits by microinjection of C...

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Bibliographic Details
Main Authors: Quanmei Yan, Quanjun Zhang, Huaqiang Yang, Qingjian Zou, Chengcheng Tang, Nana Fan, Liangxue Lai
Format: Article
Language:English
Published: SpringerOpen 2014-01-01
Series:Cell Regeneration
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2045976917300263