Generation of multi-gene knockout rabbits using the Cas9/gRNA system
The prokaryotic clustered regularly interspaced short palindromic repeat (CRISPR)-associated system (Cas) is a simple, robust and efficient technique for gene targeting in model organisms such as zebrafish, mice and rats. In this report, we applied CRISPR technology to rabbits by microinjection of C...
Main Authors: | Quanmei Yan, Quanjun Zhang, Huaqiang Yang, Qingjian Zou, Chengcheng Tang, Nana Fan, Liangxue Lai |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2014-01-01
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Series: | Cell Regeneration |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2045976917300263 |
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