Precise location of three novel linear epitopes using the generated monoclonal antibodies against the Knob domain of FAdV-4 surface structural protein, fiber1

Precise location of three novel linear epitopes using the generated monoclonal antibodies against the Knob domain of FAdV-4 surface structural protein, fiber1

BackgroundFowl adenovirus serotype 4 (FAdV-4) is the main pathogen of hepatitis-hydropericardium syndrome (HHS), which brings huge economic losses to the poultry industry worldwide. Fiber-1 protein plays an important role in viral infection and pathogenesis by binding directly to cellular receptors...

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Bibliographic Details
Main Authors: Yongxiao Chai, Qianyue Jin, Rongfang Zhu, Zhenhua Guo, Qingxia Lu, Shujun Chai, Yunrui Xing, Lu Han, Guangxu Xing, Gaiping Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
FAdV-4
fiber-1 knob protein
monoclonal antibodies
B cell epitopes
structural analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1468428/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2024.1468428/full

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