The Designer Antimicrobial Peptide A-hBD-2 Facilitates Skin Wound Healing by Stimulating Keratinocyte Migration and Proliferation

The Designer Antimicrobial Peptide A-hBD-2 Facilitates Skin Wound Healing by Stimulating Keratinocyte Migration and Proliferation

Background/Aims: Antimicrobial peptides are effective promoters of wound healing but are susceptible to degradation. In this study, we replaced the GIGDP unit on the N-terminal of the endogenous human antimicrobial peptide hBD-2 with APKAM to produce A-hBD-2 and analyzed the effect on wound healing...

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Bibliographic Details
Main Authors: Bobin Mi, Jing Liu, Yi Liu, Liangcong Hu, Yukun Liu, Adriana C. Panayi, Wu Zhou, Guohui  Liu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Antimicrobial peptide
Keratinocytes
HBD-2
A-hBD-2
Cytotoxicity
Online Access:https://www.karger.com/Article/FullText/495320

Internet

https://www.karger.com/Article/FullText/495320

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