The Link Between the Mitochondrial Fatty Acid Oxidation Derangement and Kidney Injury

The Link Between the Mitochondrial Fatty Acid Oxidation Derangement and Kidney Injury

Renal proximal tubular cells are high energy-demanding cells mainly relying on fatty acid oxidation. In stress conditions, such as transient hypoxia, fatty acid oxidation (FAO) decreases and carbohydrate catabolism fails to compensate for the energy demand. In this scenario, the surviving tubular ce...

Full description

Bibliographic Details
Main Authors: Lara Console, Mariafrancesca Scalise, Nicola Giangregorio, Annamaria Tonazzi, Maria Barile, Cesare Indiveri
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Physiology
Subjects:
mitochondria
β-oxidation
carnitine
kidney
CPT
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00794/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2020.00794/full

Similar Items