Efficient RNA interference in patients' acute lymphoblastic leukemia cells amplified as xenografts in mice
<p>Abstract</p> <p>Background</p> <p>Signaling studies in cell lines are hampered by non-physiological alterations obtained in vitro. Physiologic primary tumor cells from patients with leukemia require passaging through immune-compromised mice for amplification. The aim...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2012-03-01
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| Series: | Cell Communication and Signaling |
| Online Access: | http://www.biosignaling.com/content/10/1/8 |