Network pharmacology and experimental verification reveal the mechanism of safranal against glioblastoma (GBM)

Network pharmacology and experimental verification reveal the mechanism of safranal against glioblastoma (GBM)

IntroductionSafranal is an active component of the traditional Tibetan medicine (TTM) saffron, which has potential anticancer activity.Methods and resultsHere, we studied the therapeutic effect and mechanism of safranal on GBM. CCK-8, GBM-brain organoid coculture experiments and 3D tumour spheroid i...

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Bibliographic Details
Main Authors: Xiaobing Yang, Di Lu, Yanfei Sun, Tiandi Wei, Dulegeqi Man, Anbin Chen, Tao Luo, Feihu Zhao, Xuemeng Liu, Bo Cheng, Xu Wang, Peng Zhao, Donghai Wang, Xingang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Oncology
Subjects:
glioma
traditional tibetan medicine
safranal
Akt
network pharmacology
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1255164/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1255164/full

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