Application and prospects of single cell sequencing in tumors

Abstract Cancer is an intricate disease with inherent intra-tumor heterogeneity at the cellular level because of genetic changes and environmental differences. Cellular heterogeneity exists even within the same tumor type. Small deviations in a genome or transcriptome can lead to significant differe...

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Bibliographic Details
Main Authors: Ruo Han Huang, Le Xin Wang, Jing He, Wen Gao
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Biomarker Research
Subjects:
Online Access:https://doi.org/10.1186/s40364-021-00336-2