Complete inhibition of phosphatase and tensin homolog promotes the normal and oxygen-glucose deprivation/reperfusion-injured PC12 cells to cell death

Introduction: Lipid phosphatase and tensin homolog deleted from chromosome 10 (PTEN) antagonizes phosphoinositide 3-kinase (PI3K)/AKT cell survival pathway. The effect of PTEN inhibitors has been rarely examined on cell survival following reperfusion injury. In this study, we investigated the neurop...

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Bibliographic Details
Main Authors: Sohrab Minaei Beyrami, Mohammad Hasan Khadem Ansari, Yousef Rasemi, Nader Shakib, Pouran Karimi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2018-06-01
Series:Journal of Cardiovascular and Thoracic Research
Subjects:
Online Access:https://jcvtr.tbzmed.ac.ir/PDF/jcvtr-10-83.pdf