Priming the Abscopal Effect Using Multifunctional Smart Radiotherapy Biomaterials Loaded with Immunoadjuvants

Priming the Abscopal Effect Using Multifunctional Smart Radiotherapy Biomaterials Loaded with Immunoadjuvants

In this study, we investigate the use of multifunctional smart radiotherapy biomaterials (SRBs) loaded with immunoadjuvants for boosting the abscopal effect of local radiotherapy (RT). SRBs were designed similar to currently used inert RT biomaterials, incorporating a biodegradable polymer with rese...

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Bibliographic Details
Main Authors: Michele Moreau, Sayeda Yasmin-Karim, Sijumon Kunjachan, Neeharika Sinha, Felix Gremse, Rajiv Kumar, Kwok Fan Chow, Wilfred Ngwa
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Oncology
Subjects:
radiotherapy
immunotherapy
biomaterials
abscopal effect
antigen-presenting cell
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2018.00056/full

Internet

http://journal.frontiersin.org/article/10.3389/fonc.2018.00056/full

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