Osteocyte β1 integrin loss causes low bone mass and impairs bone mechanotransduction in mice

Osteocyte β1 integrin loss causes low bone mass and impairs bone mechanotransduction in mice

Background: The key focal adhesion protein β1 integrin plays an essential role in early skeletal development. However, roles of β1 integrin expression in osteocytes during the regulation of bone homeostasis and mechanotransduction are incompletely understood. Materials and methods: To study the in v...

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Bibliographic Details
Main Authors: Lei Qin, Tailin He, Dazhi Yang, Yishu Wang, Zhenjian Li, Qinnan Yan, Peijun Zhang, Zecai Chen, Sixiong Lin, Huanqing Gao, Qing Yao, Zhen Xu, Bin Tang, Weihong Yi, Guozhi Xiao
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Journal of Orthopaedic Translation
Subjects:
β1 integrin
Osteocyte
Bone homeostasis
Mechanotransduction
Collagen I
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X22000286

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http://www.sciencedirect.com/science/article/pii/S2214031X22000286

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