High-resolution NMR metabolomics of patients with subjective cognitive decline plus: Perturbations in the metabolism of glucose and branched-chain amino acids

High-resolution NMR metabolomics of patients with subjective cognitive decline plus: Perturbations in the metabolism of glucose and branched-chain amino acids

Background: “Subjective cognitive decline plus” (SCD plus) increases the risk of Alzheimer's disease (AD), and this may be an early stage of AD that precedes amnestic mild cognitive impairment (aMCI). We examined alterations of serum metabolites and metabolic pathways in SCD plus subjects using...

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Bibliographic Details
Main Authors: Zhongxian Yang, Jinhua Wang, Jin Chen, Min Luo, Qiuxia Xie, Yu Rong, Yi Wu, Zhen Cao, Yubao Liu
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Neurobiology of Disease
Subjects:
Subjective cognitive decline plus
Amnestic mild cognitive impairment
Metabolomics
Nuclear magnetic resonance spectroscopy
Biomarker
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996122001747

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http://www.sciencedirect.com/science/article/pii/S0969996122001747

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