Hyaluronan Regulates Neuronal and Immune Function in the Rat Small Intestine and Colonic Microbiota after Ischemic/Reperfusion Injury

Hyaluronan Regulates Neuronal and Immune Function in the Rat Small Intestine and Colonic Microbiota after Ischemic/Reperfusion Injury

Background: Intestinal ischemia and reperfusion (IRI) injury induces acute and long-lasting damage to the neuromuscular compartment and dysmotility. This study aims to evaluate the pathogenetic role of hyaluronan (HA), a glycosaminoglycan component of the extracellular matrix, as a modulator of the...

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Bibliographic Details
Main Authors: Annalisa Bosi, Davide Banfi, Michela Bistoletti, Lucia Martina Catizzone, Anna Maria Chiaravalli, Paola Moretto, Elisabetta Moro, Evgenia Karousou, Manuela Viola, Maria Cecilia Giron, Francesca Crema, Carlo Rossetti, Giorgio Binelli, Alberto Passi, Davide Vigetti, Cristina Giaroni, Andreina Baj
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cells
Subjects:
intestinal ischemia/reperfusion injury
enteric nervous system
intestinal neuromuscular function
microbiota
TLRs
Online Access:https://www.mdpi.com/2073-4409/11/21/3370

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https://www.mdpi.com/2073-4409/11/21/3370

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