Combined analysis of plasma metabolome and intestinal microbiome sequencing to explore jiashen prescription and its potential role in changing intestine–heart axis and effect on chronic heart failure

Combined analysis of plasma metabolome and intestinal microbiome sequencing to explore jiashen prescription and its potential role in changing intestine–heart axis and effect on chronic heart failure

BackgroundHeart failure (HF) is a syndrome with global clinical and socioeconomic burden worldwide owing to its poor prognosis. Jiashen Prescription (JSP), a traditional Chinese medicine (TCM) formula, exhibits unambiguous effects on treating HF. Previously, we have reported that underlying mechanis...

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Bibliographic Details
Main Authors: Xialian Cui, Yangyan Su, Xiaotong Huang, Jiaping Chen, Jiang Ma, Peiran Liao, Xin He
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
heart failure
jiashen prescription
intestinal microbiota
plasma metabolomics
weighted gene co-expression network analysis (WGCNA)
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1147438/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2023.1147438/full

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