Hydrogen sulfide reduces oxidative stress in Huntington’s disease via Nrf2

Hydrogen sulfide reduces oxidative stress in Huntington’s disease via Nrf2

The pathophysiology of Huntington’s disease involves high levels of the neurotoxin quinolinic acid. Quinolinic acid accumulation results in oxidative stress, which leads to neurotoxicity. However, the molecular and cellular mechanisms by which quinolinic acid contributes to Huntington’s disease path...

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Bibliographic Details
Main Authors: Zige Jiang, Dexiang Liu, Tingting Li, Chengcheng Gai, Danqing Xin, Yijing Zhao, Yan Song, Yahong Cheng, Tong Li, Zhen Wang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications
Series:Neural Regeneration Research
Subjects:
apoptosis
cystathionine-β-synthase
nuclear factor erythroid 2-related factor 2
huntington’s disease
hydrogen sulfide
mitochondrion
neuroplasticity
oxidative stress
quinolinic acid
reactive oxygen species
Online Access:https://journals.lww.com/10.4103/NRR.NRR-D-23-01051

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https://journals.lww.com/10.4103/NRR.NRR-D-23-01051

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