A Non-canonical Pathway with Potential for Safer Modulation of Transforming Growth Factor-β1 in Steroid-Resistant Airway Diseases

A Non-canonical Pathway with Potential for Safer Modulation of Transforming Growth Factor-β1 in Steroid-Resistant Airway Diseases

Summary: Impaired therapeutic responses to anti-inflammatory glucocorticoids (GC) in chronic respiratory diseases are partly attributable to interleukins and transforming growth factor β1 (TGF-β1). However, previous efforts to prevent induction of GC insensitivity by targeting established canonical...

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Bibliographic Details
Main Authors: Meina Li, Christine R. Keenan, Guillermo Lopez-Campos, Jonathan E. Mangum, Qianyu Chen, Danica Prodanovic, Yuxiu C. Xia, Shenna Y. Langenbach, Trudi Harris, Vinzenz Hofferek, Gavin E. Reid, Alastair G. Stewart
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219300240

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http://www.sciencedirect.com/science/article/pii/S2589004219300240

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