Leukotriene A4 hydrolase (LTA4H rs17525495) gene polymorphisms and paradoxical reactions in extrapulmonary tuberculosis

Abstract Paradoxical reactions (PRs) are poorly studied complex immunological phenomena, among patients with tuberculosis (TB). When PRs involves critical structures like the central nervous system (CNS), immunomodulatory therapy is often required. Predictors for PRs in TB to pre-empt appropriate tr...

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Bibliographic Details
Main Authors: Selwyn Selva Kumar, Raja Solomon, Priyanka Gautam, Leeberk Raja Inbaraj, Ajith Sivadasan, Joy Sarojini Michael, Rajiv Karthik, George M. Varghese, Christhunesa S. Christudass, Prasanna Samuel, Abi Manesh
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-30923-2