Nutrients required for phospholipid synthesis are lower in blood and cerebrospinal fluid in mild cognitive impairment and Alzheimer's disease dementia
Abstract Introduction Synaptic membrane formation depends on nutrients that fuel metabolic pathways for the synthesis of constituent phospholipids. Consequently, insufficient availability of such nutrients may restrict membrane formation and contribute to synaptic dysfunction in Alzheimer's dis...
Main Authors: | Nick vanWijk, Rosalinde E.R. Slot, Flora H. Duits, Marieke Strik, Egbert Biesheuvel, John W.C. Sijben, Marinus A. Blankenstein, Jörgen Bierau, Wiesje M. van derFlier, Philip Scheltens, Charlotte E. Teunissen |
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Format: | Article |
Language: | English |
Published: |
Wiley
2017-01-01
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Series: | Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring |
Subjects: | |
Online Access: | https://doi.org/10.1016/j.dadm.2017.04.005 |
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