Diagnostic Performance of Immunohistochemistry Compared to Molecular Techniques for Microsatellite Instability and p53 Mutation Detection in Endometrial Cancer

Diagnostic Performance of Immunohistochemistry Compared to Molecular Techniques for Microsatellite Instability and p53 Mutation Detection in Endometrial Cancer

Molecular algorithms may estimate the risk of recurrence and death for patients with endometrial cancer (EC) and may impact treatment decisions. To detect microsatellite instabilities (MSI) and p53 mutations, immunohistochemistry (IHC) and molecular techniques are used. To select the most appropriat...

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Bibliographic Details
Main Authors: Sylvie Streel, Alixe Salmon, Adriane Dheur, Vincent Bours, Natacha Leroi, Lionel Habran, Katty Delbecque, Frédéric Goffin, Clémence Pleyers, Athanasios Kakkos, Elodie Gonne, Laurence Seidel, Frédéric Kridelka, Christine Gennigens
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
endometrial cancer
molecular classification
immunohistochemistry
polymerase chain reaction
next generation sequencing method
p53
Online Access:https://www.mdpi.com/1422-0067/24/5/4866

Internet

https://www.mdpi.com/1422-0067/24/5/4866

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