Delineating an Epigenetic Continuum for Initiation, Transformation and Progression to Breast Cancer

Aberrant methylation of promoter CpG islands is a hallmark of human cancers and is an early event in carcinogenesis. We examined whether promoter hypermethylation contributes to the pathogenesis of benign breast lesions along a progression continuum to invasive breast cancer. The exploratory study c...

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Bibliographic Details
Main Authors: Maria J. Worsham, Usha Raju, Josena K. Stephen, Kang Mei Chen
Format: Article
Language:English
Published: MDPI AG 2011-03-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/3/2/1580/