A high-resolution route map reveals distinct stages of chondrocyte dedifferentiation for cartilage regeneration
Abstract Articular cartilage damage is a universal health problem. Despite recent progress, chondrocyte dedifferentiation has severely compromised the clinical outcomes of cell-based cartilage regeneration. Loss-of-function changes are frequently observed in chondrocyte expansion and other pathologi...
Main Authors: | , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-04-01
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Series: | Bone Research |
Online Access: | https://doi.org/10.1038/s41413-022-00209-w |