Thrombus remodelling by reversible and irreversible P2Y12 inhibitors

Pharmacological inhibition of the platelet ADP-receptor P2Y12 is a cornerstone in the prevention of atherothrombotic events in adult patients with acute coronary syndrome (ACS). Thienopyridines such as clopidogrel and prasugrel exert their antithrombotic effect by means of active metabolites that ir...

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Bibliographic Details
Main Authors: Kjersti Tunströmer, Lars Faxälv, Pia Larsson, Tomas L. Lindahl, Niklas Boknäs
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Platelets
Subjects:
Online Access:http://dx.doi.org/10.1080/09537104.2022.2157805